成果展示

英文论文


(1) Xiao, Y., Jin, W., Ju, L. et al. Tracking single-cell evolution using clock-like chromatin accessibility loci. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02241-z

(2) Xiao Y, Jin W, Qian K, et al. Integrative Single Cell Atlas Revealed Intratumoral Heterogeneity Generation from an Adaptive Epigenetic Cell State in Human Bladder Urothelial Carcinoma. Adv. Sci. 2024, 2308438. doi: 10.1002/advs.202308438.

(3) Zhang R, Jiang W, Wang G, et al. Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase. Commun Biol. 2024 Feb 29;7(1):245. doi: 10.1038/s42003-024-05935-x.

(4) Li, M., Yu, J., Ju, L. et al. USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer. Cell Death Dis 15, 44 (2024). doi:10.1038/s41419-024-06446-7.

(5) Zhou, F., Deng, Z., Shen, D. et al. DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11. Oncogene (2024). https://doi.org/10.1038/s41388-023-02932-y

(6) Yu, J., Li, M., Ju, L. et al. TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC. Oncogene (2023). https://doi.org/10.1038/s41388-023-02922-0

(7) Wang, G, Jin, W, Xu, Z, et al. Urine-based liquid biopsy in bladder cancer: Opportunities and challenges. Clin Transl Disc. 2023; 3:e176. https://doi.org/10.1002/ctd2.176

(8) Wang, Y., Ju, L., Wang, G. et al. DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nat Commun 14, 2421 (2023). https://doi.org/10.1038/s41467-023-38160-x

(9) Deng Z, Shen D, Yu M, Zhou F, et al. Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways. Cell Death Discovery. 2023 Jul 1;9(1):214. doi: 10.1038/s41420-023-01508-9. PMID: 37393350; PMCID: PMC10314945.

(10) Shen, D., Deng, Z., Liu, W. et al. Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis. Cell Death Dis 14, 246 (2023). https://doi.org/10.1038/s41419-023-05770-8

(11) Zou C, Ji C, Zhu Y, et al. Effects of Freezing and Rewarming Methods on RNA Quality of Blood Samples. Biopreserv Biobank. 2023;21(2):176-183. doi:10.1089/bio.2022.0007

(12) Du W, Wang T, Zhang W, Xiao Y and Wang X (2022), Genetically supported causality between benign prostate hyperplasia and urinary bladder neoplasms: A mendelian randomization study. Front. Genet. 13:1016696. doi: 10.3389/fgene.2022.1016696.

(13) Liu W#, Shen D#, Ju L#, Zhang R#, Du W, Jin W, Xiong K, Wang G, Qian K, Zhang Y*, Xiao Y*, Wang X*. MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3. Oncogene. 2022 Oct ;41(41):4606-4617. doi: 10.1038/s41388-022-02456-x. 

(14) Xiao Y#, Wang X#, Weng H#, Ding Z#, Qian K#, Jin W, Lu S, Ju L, He Z, Wang G, Xie X, Liu D, Fan Z, Wu K, Li S, Guo H, Qian G, Jiang W, Leng Y, Zhao J, Cao X, Peng M, Jiang C*, Li L*, Zhang Y*, Wang X*. Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation.Clinical and Translational Medicine. 2022 Sep;12(9):e1015. doi: 10.1002/ctm2.1015.

(15) Xiao Y#, Ju L#, Qian K#, Jin W#, Wang G, Zhao Y, Jiang W, Liu N, Wu K, Peng M, Cao R, Li S, Shi H, Gong Y, Zheng H, Liu T, Luo Y, Ma H, Chang L, Li G, Cao X, Tian Y, Xu Z, Yang Z, Shan L, Guo Z, Yao D, Zhou X, Chen X, Guo Z, Liu D, Xu S, Ji C, Yu F, Hong X, Luo J, Cao H, Zhang Y*, Wang X*. Non-invasive diagnosis and surveillance of bladder cancer with driver and passenger DNA methylation in a prospective cohort study. Clinical and Translational Medicine. 2022 Aug;12(8):e1008. doi: 10.1002/ctm2.1008.

(16) Liu N, Luo Y, Zhu Y, et al. Effects of Warm Ischemia Time, Cryopreservation, and Grinding Methods on RNA Quality of Mouse Kidney Tissues. Biopreserv Biobank. 2021;19(4):306-311. doi:10.1089/bio.2020.0129

(17) Xiong Y, Ju L, Yuan L, Chen L, Wang G, Xu H, Peng T, Luo Y, Xiao Y*, Wang X*. KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer. Oncogene. 2021 Mar;40(9):1595-1608. doi: 10.1038/s41388-020-01634-z. 

(18) Wang Z#, Hu W#, You W#, Huang G, Tian W, Huselstein C,Wu C,Xiao Y, Chen Y*,Wang X*. Antibacterial and angiogenic wound dressings for chronic persistent skin injury. Chemical Engineering Journal. 2021 Jan 15;404:126525. doi:org/10.1016/j.cej.2020.126525

(19) Chen S#, He Z#, Peng T, Zhou F, Wang G, Qian K, Ju L, Xiao Y, Wang X*. PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability. JCI Insight. 2021 Oct 8;6(19):e145172. doi: 10.1172/jci.insight.145172.

(20) Liu R, Qian K, Xiao Y*, Jiang W*. Generation of two induced pluripotent stem cell lines from blood cells of a prostate cancer patient carrying germline mutation in CHEK2. Stem Cell Research. 2021 May;53:102299. doi: 10.1016/j.scr.2021.102299. 

(21) Guo S#, Huang H#, Zeng W, Jiang Z, Wang X, Huang W, Wang X*. Facile cell patterning induced by combined surface topography and chemistry on polydopamine-defined nanosubstrates. Nanotechnology. 2021 Apr 2;32(14):145303. doi: 10.1088/1361-6528/abd6d2. 

(22) Shen D#, Ju L#, Zhou F#, Yu M, Ma H, Zhang Y, Liu T, Xiao Y*, Wang X*, Qian K*. The inhibitory effect of melatonin on human prostate cancer. Cell Communication and Signaling. 2021 Mar 15;19(1):34. doi: 10.1186/s12964-021-00723-0.

(23) Xu H#, Ju L#*, Xiong Y#, Yu M, Zhou F, Qian K, Wang G, Xiao Y, Wang X*. E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability. Cell Death & Disease. 2021 Mar 4;12(3):239. doi: 10.1038/s41419-021-03521-1.

(24) Qian K#, Wang G#, Ju L#, Liu J, Luo Y, Wang Y, Peng T, Chen F, Zhang Y*, Xiao Y, Wang X*. A novel germline EGFR variant p. R831H causes predisposition to familial CDK12-mutant prostate cancer with tandem duplicator phenotype. Oncogene. 2020 Oct;39(44):6871-6878. doi: 10.1038/s41388-020-01476-9.

(25) Hu W, Wang Z, Zha Y, Gu X, You W, Xiao Y, Wang X, Zhang S*, Wang J*.High Flexible and Broad Antibacterial Nanodressing Induces Complete Skin Repair With Angiogenic and Follicle Regeneration. Advanced Healthcare Materials. 2020 May 6;e2000035. doi: 10.1002/adhm.202000035.

(26) Wang Z, Hu W, Du Y, Xiao Y, Wang X*, Zhang S, Wang J*, Mao C*. Green Gas-Mediated Cross-Linking Generates Biomolecular Hydrogels With Enhanced Strength and Excellent Hemostasis for Wound Healing.ACS Applied Materials & Interfaces . 2020 Mar 25;12(12):13622-13633. doi: 10.1021/acsami.9b21325.

(27) Luo Y, Ju L, Wang G, Chen C, Wang Y, Chen L, Zhang Y, Xiao Y*, Wang X*. Comprehensive Genomic Profiling of Urothelial Carcinoma Cell Lines Reveals Hidden Research Bias and Caveats. Clinical and Translational Medicine. 2020 Jan;10(1):294-296. doi: 10.1002/ctm2.36.

(28) Ge Q, Lu M, Ju L, Qian K, Wang G, Wu CL, Liu X, Xiao Y*, Wang X*. miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladder cancer. International Journal of Cancer. 2019 Jun 15;144(12):3043-3055. doi: 10.1002/ijc.32036. 



中文论文


(1) 张鑫,肖宇,钱开宇,夏彩霞*,朱源*.抗凝血离心沉淀红细胞中残留基因组DNA的质量分析【J】.转化医学杂志,2023,12(2);80-85.

(2) 张鑫,邹聪,刘南,钱开宇,肖宇,朱源*.尿液游离核酸的大小分布情况及检测方式选择【J】.中国医药生物技术,2023,18(2);122-126.

(3) 王刚,许紫琳,曹馨月,鞠林高,钱开宇,肖宇*.在研究生教学中开展人类遗传资源医学教育的思考【J】.中国继续医学教育,2023,15(6);159-163.

(4) 张姗姗,彭宏威,邹聪, 刘南*.底部预置二维码冻存管在生物样本存储中的应用方法【J】.中国医药生物技术,2021,16(1);73-77.

(5) 彭宏威,张姗姗,周宗宁,陈文,许紫琳,陈杭,邹聪,李刚,胡莹,钱开宇*.玻璃化法冻存组织样本的研究进展【J】.转化医学杂志,2020,9(1);41-44.

(6) 钱开宇, 朱源, 曹馨月, 肖宇. 加强伦理委员会建设,促进生物样本库发展【J】. 转化医学杂志, 2018,7(01):14-16.